Streamlined Quantitative-BOLD provides a method for quantifying brain oxygen metabolism, in particular, deoxygenated blood volume and oxygen extraction fraction, based on linear fitting of values obtained from an asymmetric spin-echo sequence. It is possible that a curve-fitting approach may yield more robust values for these parameters. This study investigated the feasibility of estimating brain metabolic and vascular parameters through a Bayesian framework, through simulations, and analysis of patient data. It was found that under the current model, simultaneous estimation of oxygen extraction fraction and blood volume was not reliable, suggesting a limit to the model or acquisition protocol.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords