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Abstract #5290

Contrary Effect of Stressful vs. Non-stressful Striped Patterns on Human Visual Cortical Functional Connectivity

Jie Huang1 and David C. Zhu1,2

1Department of Radiology, Michigan State University, East Lansing, MI, United States, 2Department of Psychology, Michigan State University, East Lansing, MI

Areas across the visual cortex are functionally connected. A stressful striped pattern induces perceptual illusions/distortions and visual discomfort in most people, headaches in patients with migraine, and seizures in patients with photosensitive epilepsy. In contrary, a non-stressful striped pattern does not induce such effects. This study found that a 25-min visual stimulation showed a significantly contrary effect of the stressful vs. non-stressful striped patterns on human visual cortical functional connectivity (FC). To the contrary of the strengthening effect of the stressful striped pattern on the FC, the non-stressful striped pattern showed a weakening effect on the FC.

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