We measured the association between aerobic fitness and cerebral blood flow (CBF) and cerebrovascular reactivity (CVR) in young, healthy adults using multiple inversion time (MTI) arterial spin labelling (ASL), with a hypercapnic challenge to assess CVR. The results show that higher fitness is associated with lower baseline CBF and greater CVR. Although studies with a larger sample size are required to clarify the relationship between fitness and cerebrovascular function in early adulthood, the current results suggest that aerobic fitness may promote vascular efficiency and reserve.
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