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Abstract #5320

fMRI-based brain responses to bitter and sucrose gustatory stimulation for nutrition research in the minipig model

Nicolas Coquery1, Paul Meurice1, Régis Janvier1, Eric Bobillier1, Stéphane Quellec2, Hervé Saint-Jalmes3, and David Val-Laillet1

1UR1341 ADNC, INRA, Saint-Gilles, France, 2UR TERE, IRSTEA, Rennes, France, 3UMR1099, INSERM, Rennes, France

The minipig model is of high interest for brain research in nutrition and associated pathologies considering the similarities to human nutritional physiology, brain structures and functions1,2 . In the context of a gustatory stimulation paradigm, fMRI can provide crucial information about the sensory, cognitive and hedonic integration of exteroceptive stimuli in healthy and pathological nutritional conditions. To date, this is the first intent to describe gustatory stimulation in minipigs using fMRI.

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