Abstract #5346

Voxel-level comparison of regional neural activity in patients with type 2 diabetes mellitus

Dong Zhang¹, Changzheng Shi¹, Rong Ma¹, Zhongping Zhang², and Liangping Luo¹

¹Medical Imaging Center, The First Affiliated Hospital of Jinan University, Guangzhou, People's Republic of China, ²MR Research China, GE Healthcare, Beijing

People with high risk of diabetes exhibited decreased ReHo in right temporal lobes, left pallidum/ lenticular nucleus/insula/Heschl gyrus and left cingulate cortex and declined fALFF in left Heschl gyrus, left supramarginal gyrus and left cingulate cortex, which is consistent with type 2 diabetes mellitus (T2DM) patients. These abnormal regions may be regarded as the endophenotype of T2DM in resting-state BOLD-fMRI.

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