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Abstract #5346

Voxel-level comparison of regional neural activity in patients with type 2 diabetes mellitus

Dong Zhang1, Changzheng Shi1, Rong Ma1, Zhongping Zhang2, and Liangping Luo1

1Medical Imaging Center, The First Affiliated Hospital of Jinan University, Guangzhou, People's Republic of China, 2MR Research China, GE Healthcare, Beijing

People with high risk of diabetes exhibited decreased ReHo in right temporal lobes, left pallidum/ lenticular nucleus/insula/Heschl gyrus and left cingulate cortex and declined fALFF in left Heschl gyrus, left supramarginal gyrus and left cingulate cortex, which is consistent with type 2 diabetes mellitus (T2DM) patients. These abnormal regions may be regarded as the endophenotype of T2DM in resting-state BOLD-fMRI.

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