Abstract #5356

Multi-Echo EPI improves olfaction-related brain activation

Sonja Blankenagel^1,2, Ana Beatriz Solana³, Brice Fernandez⁴, Christoph Hofstetter⁵, Andreas Dunkel⁵, Thomas Hofmann⁵, Hans Hauner^6,7, and Jessica Freiherr^1,2

¹Fraunhofer Institute for Process Engineering and Packaging (IVV), Freising, Germany, ²Diagnostic and Interventional Neuroradiology, RWTH Aachen University, Aachen, Germany, ³GE Global Research, Munich, Germany, ⁴GE Healthcare, Orsay, France, ⁵Food Chemistry and Molecular Sensory Science, Technical University of Munich, Freising, Germany, ⁶ZIEL Institute for Food and Health, Clinical Nutritional Medicine, Technical University of Munich, Munich, Germany, ⁷Institute of Nutritional Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany

Multi‑echo planar imaging (MEPI) was explored regarding its ability to overcome the limitations of conventional EPI imaging in studies related to olfaction. MEPI offers great sensibility even in brain regions, which are affected by susceptibility artifacts in EPI imaging. Five subjects were scanned using an event-related olfactory task with both sequences. The subsequent comparison shows that three echoes MEPI has advantages regarding olfaction-related brain activation compared to single echo EPI.

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