We characterized depth-dependent laminar profiles of surround suppression in human early visual cortex with high-resolution 7T fMRI. In a block-design participants viewed circular target stimuli (gratings defined by sinusoidal luminance modulation) surrounded by an annulus with a grating either parallel or orthogonal to the target grating. The surround was placed either adjacent to the target grating (Near) or separated from the target by 2° of visual angle (Far). Results show a similar activation profile for Parallel and Orthogonal conditions in the Far condition across depth. For the Near condition, contextual modulation occurred more in deep, rather than superficial layers.