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Abstract #5367

Evidence of modulation of laminar profiles by contextual modulation in V1 using high-resolution fMRI

Kimberly B Weldon1, Michael-Paul Schallmo2, Philip C Burton3, Andrea N Grant4, and Cheryl A Olman1

1Department of Psychology, University of Minnesota, Minneapolis, MN, United States, 2Department of Psychology, University of Washington, Seattle, WA, United States, 3Office of the Associate Dean for Research, University of Minnesota, Minneapolis, MN, United States, 4Department of Neuroscience, University of Minnesota, Minneapolis, MN, United States

We characterized depth-dependent laminar profiles of surround suppression in human early visual cortex with high-resolution 7T fMRI. In a block-design participants viewed circular target stimuli (gratings defined by sinusoidal luminance modulation) surrounded by an annulus with a grating either parallel or orthogonal to the target grating. The surround was placed either adjacent to the target grating (Near) or separated from the target by 2° of visual angle (Far). Results show a similar activation profile for Parallel and Orthogonal conditions in the Far condition across depth. For the Near condition, contextual modulation occurred more in deep, rather than superficial layers.

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