Abstract #5376

The Early Global Function Connectivity Stability in Infants during the Neonatal Period

Yue Cai^1,2, Yuan Shi³, Yang Fan⁴, Wei Gao^5,6, and Jiahong Gao²

¹Department of Biomedical Engineering, Peking University, beijing, People's Republic of China, ²Center for MRI Research, Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, People's Republic of China, ³Daping Hospital, Third Military Medical University, Daping Hospital, Third Military Medical University, Chongqing, People's Republic of China, ⁴MR Research China, GE Healthcare, Beijing, People's Republic of China, ⁵Biomedical Imaging Research Institute (BIRI), Department of Biomedical Sciences and Imaging, Cedars-Sinai Medical Center, los angeles, CA, United States, ⁶Department of Radiology and Biomedical Research Imaging Center, University of North Carolina Chapel Hill, United States

This study proposes an improved method named global functional connectivity stability (GFCS) to quantify the brain dynamic functional connectivity at a voxel-wise level. The GFCS was applied to investigate the overall functional connectivity stability and its correlation with time in infants during the period from late preterm to the term equivalent age (TEA). It is shown that infants presented high functional stability predominantly in the sensorimotor areas, temporal lobe, posterior cingulate cortex (PCC) and medial prefrontal cortex. With time, the frontal areas appeared more variable while the sensorimotor cortex appeared more stable in infants during the neonatal period.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.