The aim of this study was to explore the different subtypes and immunohistochemical expression of breast cancer in improved multi-parametric MR imaging. By introducing the free breathing of ultrafast temporal resolution dynamic VIBE (TWIST-VIBE) and readout segmentation of long variable echo-trains (RESOLVE) techniques, quantitative pharmacokinetic (PK), semi-quantitative DCE-MRI based on curve of time concentration and diffusion parameters were extracted to analyze it. The results show that significant differences in multi parametric parameters Kep and rADC among the different subtypes of Breast cancer. Those parameters were hopeful to be a non-invasive measurement for assessing the subtypes and the biology, histological features of breast cancer.
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