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Abstract #5426

Visualization of the VIM Thalamic Nucleus using Synthesized MPRAGE Images

Jiachen Zhuo1, Steven Roys1, John Hebel1, Erma Owens1, Prashant Raghavan1, Dheeraj Gandhi1, and Rao P Gullapalli1

1Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, MD, United States

The ventral intermediate nucleus (VIM) of the thalamus is a highly effective target for treatment of essential tremor (ET). Visualization of VIM is however challenging due to the lack of T1 or T2 MRI contrast between the various thalamic nuclei. In this study, we used synthesized MPRAGE images with varied inversion time (TI) (SynTI images) to visualize the VIM for pre-surgical planning in MRgFUS treatment of ET. Verification based on 24hr post-treatment lesion location on four patients showed good agreement from the identified VIM with lesion center.

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