In this case study we show the dependence of the lead transfer function and the RF-induced power deposition (P) on the presence of heterogeneous tissues around of the lead tip. Depending on the lead length, our results shows a dramatic non-linear dependence of P on a small volume of a different tissue surrounding the lead tip, i.e., a fatty pocket, when using a TF derived in a homogeneous media. Thus, using TFs derived in a homogeneous media can result in large systematic errors in predicting P, and consequently the lead tip heating, of AIMDs inside a human body.
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