Abstract #5506

Ultra-short echo STEAM with TE of 3 ms improves 1H-MRS based lipid quantification and allows fast localization of 31P metabolite signals in the liver at 7T

Martin Gajdošík^1,2, Marek Chmelík^3,4, Lorenz Pfleger^1,2, Anton Luger², Siegfried Trattnig^1,4, and Martin Krššák^1,2

¹High-field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, ²Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria, ³Clinical Molecular Imaging, Karl Landsteiner Institute, Vienna, Austria, ⁴Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria

Liver fat quantification with in vivo ¹H-MR spectroscopy is challenging at ultra-high fields also due to very short T₂ times. Ultra-short TE localized sequence using Gaussian pulses with TE of 3ms was developed and its advantages could be utilized also with ³¹P-MR spectroscopy. Our data showed, that localization was feasible in large homogeneous tissues such as liver providing liver fat measurement with unprecedented precision. The detection of ³¹P signals was feasible and resulted in high spectral resolution in acceptable time.

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