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Abstract #5506

Ultra-short echo STEAM with TE of 3 ms improves 1H-MRS based lipid quantification and allows fast localization of 31P metabolite signals in the liver at 7T

Martin Gajdošík1,2, Marek Chmelík3,4, Lorenz Pfleger1,2, Anton Luger2, Siegfried Trattnig1,4, and Martin Krššák1,2

1High-field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, 2Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria, 3Clinical Molecular Imaging, Karl Landsteiner Institute, Vienna, Austria, 4Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria

Liver fat quantification with in vivo 1H-MR spectroscopy is challenging at ultra-high fields also due to very short T2 times. Ultra-short TE localized sequence using Gaussian pulses with TE of 3ms was developed and its advantages could be utilized also with 31P-MR spectroscopy. Our data showed, that localization was feasible in large homogeneous tissues such as liver providing liver fat measurement with unprecedented precision. The detection of 31P signals was feasible and resulted in high spectral resolution in acceptable time.

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