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Abstract #5508

J-difference semi-LASER for GABA editing

Ralph Noeske1

1GE Healthcare, Berlin, Germany

The performance of a J-difference spectral editing technique based on the across vendor implementation of semi-LASER with high bandwidth GOIA-WURST adiabatic gradient modulated refocusing pulses for a GABA+ and macromolecule-suppressed GABA protocol was investigated. Phantom measurements show a TE dependence of the edited 3ppm GABA signal that allows using the longer TE of 80ms to implement a macromolecular-suppressed protocol with higher signal compared to a PRESS based implementation.

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