Abstract #5539

Controlling Brain Infusion Distributions: Moving from Surgical Planning to Real-Time MR Guidance

Martin Brady¹, Raghu Raghavan¹, Andrew L Alexander^2,3, and Walter F Block^2,3,4

¹Therataxis, Baltimore, MD, United States, ²TherVoyant, Madison, WI, United States, ³Medical Physics, University of Wisconsin- Madison, Madison, WI, United States, ⁴Biomedical Engineering, University of Wisconsin- Madison, Madison, WI, United States

The hetergeneity of the brain makes designing a desired end drug distribution through pressurized catheters difficult. We present a method to utilize real-time MR monitoring of a co-infused Gd tracer during initial stages of the infusion to derive a real-time 3D estimate of the velocity front. We also describe a new algorithm that uses the velocity front to provide surgical feedback on the likely final infusion distribution.

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