Abstract #5575

Impact of Abdominal Magnetic Resonance Imaging on DNA Double Strand-Breaks in Human Blood Lymphocytes

Saravanabavaan Suntharalingam¹, Emil Mladenov², Georg Iliakis², Michael Forsting¹, Oliver Kraff^3,4, Harald H. Quick^3,4, and Kai Nassenstein¹

¹Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, Germany, ²Institute of Medical Radiation Biology, University Hospital Essen, Essen, Germany, ³Erwin L. Hahn Institute for Magnetic Resonance Imaging, University Hospital Essen, Essen, Germany, ⁴High Field and Hybrid MR Imaging, University Hospital Essen, Essen, Germany

Magnetic resonance imaging is considered to be a safe alternative to other imaging techniques that use ionizing radiation, such as computed tomography. Initially driven by X-ray and CT imaging studies, within the recent years different in vitro and in vivo studies analyzed the impact of MR imaging on DNA integrity in human lymphocytes but reported contradictory results. In this study on patients referred to clinical abdominal MRI, γ-H2AX immunofluorescence microscopy was used to determine DNA integrity. No evidence of DNA damage induced by abdominal MRI in a clinical setting was found.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.