Meeting Banner
Abstract #0046

Covariation of pulse oximetry amplitude and BOLD fMRI across vigilance states

Catie Chang1, Pinar Ozbay1, Jacco de Zwart1, Dante Picchioni1, Miranda Chappel-Farley1, Hendrik Mandelkow1, and Jeff Duyn1

1NIH, Bethesda, MD, United States

While pulse oximetry (PO) is often used with fMRI to provide the timing of heart beats, few studies have focused on fluctuations in the amplitude of PO waveform in the context of fMRI signals. Here, we examine correlations between spontaneous fMRI signals and PO amplitude (POA) variations, observing a strong dependence on vigilance state. During alertness, POA-fMRI correlations were weaker but encompassed regions comprising the default-mode network. During drowsiness and NREM sleep, POA co-varied extensively with BOLD signals across the brain.

This abstract and the presentation materials are available to members only; a login is required.

Join Here