Neuroimaging techniques provide a unique window on the study of human brain function in healthy as well as pathological conditions. Intra-cranial electrocorticography (ECoG) at high frequency broadband power is associated with positive blood-oxygenation-level-dependent signal, but the electrophysiological correlates of negative BOLD signals are are less well understood. Here we investigate the relationship between negative BOLD and neuronal population activity measured with ECoG, in humans, using a paradigm that excludes blood stealing as a source of negative BOLD signal.
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