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Abstract #0163

Quantification of Phosphatidylcholine in the gall bladder using 31P MRSI suggest differences in biliary disorders: A Pilot Study.

Lorenz Pfleger1,2, Emina Halilbasic3, Martin Gajdošík1,4, Marek Chmelík2,5,6, Sigfried Trattnig2,7, Michael Trauner3, and Martin Krššák1,2

1Division of Endocrinology and Metabolism, Department of Medicine III, Medical University of Vienna, Vienna, Austria, 2High-field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, 3Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria, 4Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States, 5Faculty of Healthcare, University of Prešov, Prešov, Slovakia, 6Department of Radiology, General Hospital of Levoča, Levoča, Slovakia, 7Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria

This study focuses on quantification of phosphatidylcholine (PtdC) in the gall bladder and investigates concentration differences between biliary pathologies and healthy subjects. Significant different PtdC content was detected in patients suffering from primary sclerosing cholangitis (PSC). Subjects with primary biliary cholangitis (PBC) showed high variances in PtdC concentration. Even though, the PSC and control group are relatively small our results justify for further ongoing studies on this topic.

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