Abstract #0163

Quantification of Phosphatidylcholine in the gall bladder using 31P MRSI suggest differences in biliary disorders: A Pilot Study.

Lorenz Pfleger^1,2, Emina Halilbasic³, Martin Gajdošík^1,4, Marek Chmelík^2,5,6, Sigfried Trattnig^2,7, Michael Trauner³, and Martin Krššák^1,2

¹Division of Endocrinology and Metabolism, Department of Medicine III, Medical University of Vienna, Vienna, Austria, ²High-field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, ³Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria, ⁴Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States, ⁵Faculty of Healthcare, University of Prešov, Prešov, Slovakia, ⁶Department of Radiology, General Hospital of Levoča, Levoča, Slovakia, ⁷Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria

This study focuses on quantification of phosphatidylcholine (PtdC) in the gall bladder and investigates concentration differences between biliary pathologies and healthy subjects. Significant different PtdC content was detected in patients suffering from primary sclerosing cholangitis (PSC). Subjects with primary biliary cholangitis (PBC) showed high variances in PtdC concentration. Even though, the PSC and control group are relatively small our results justify for further ongoing studies on this topic.

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