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Abstract #0170

Spatially-selective excitation using a tailored nonlinear ΔB0 pattern generated by an integrated multi-coil ΔB0/Rx array

Jason Stockmann1,2, Nicolas S Arango3, Benedikt Poser4, Thomas Witzel1,2, Jacob White3, Lawrence L Wald1,2,5, and Jonathan R Polimeni1,2,5

1Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, 2Harvard Medical School, Boston, MA, United States, 3Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA, United States, 4Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, Netherlands, 5Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, United States

Multi-coil ΔB0 shim arrays have recently been used for zoomed imaging of target ROIs in mice, providing improved acquisition efficiency without the high SAR, long RF pulses, and other limitations of conventional selective excitation methods that rely solely on linear gradients. We extend this work to zoomed 3D EPI in humans using an integrated ΔB0/Rx array coil to dynamically switch-on a static, spatially-tailored nonlinear ΔB0 pattern during RF excitation. Proof-of-concept selective excitations of the occipital visual cortex and the peripheral cerebrum are shown, with strong correspondence to the target patterns. Four-fold in-plane undersampled EPI of occipital visual cortex demonstrates the method’s potential for efficient high-resolution neuroimaging.

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