Abstract #0197

Correlations of T1ρ with properties of articular cartilage depend on the spin-lock amplitude and orientation of the sample

Mikko Johannes Nissi¹, Isabel Stavenuiter^1,2, and Nina Hänninen³

¹Department of applied physics, University of Eastern Finland, Kuopio, Finland, ²Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, Netherlands, ³Research Unit of Medical Imaging, Physics and Technology, University of Oulu, Oulu, Finland

Several studies have reported different findings on the correlations of the CW-T1ρ relaxation time in articular cartilage with its different properties. Most studies agree on the sensitivity of CW-T1ρ to cartilage proteoglycans, although reports specifically against this also exist. Furthermore, CW-T1ρ has been connected to the collagen network properties and also correlated with T2 relaxation time. Orientation dependence of CW-T1ρ has been reported, as well as its dependence on the spin-locking amplitude. This study aims to combine all of these aspects in a single study.

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