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Abstract #0286

Cardiac Phase-resolved Late-Gadolinium Enhancement Imaging

Sebastian Weingärtner1,2,3, Burhaneddin Yaman1,2, Chetan Shenoy4, Marcel Prothmann5, Felix Wenson5, Jeanette Schulz-Menger5,6, and Mehmet Akcakaya1,2

1Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN, United States, 2Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States, 3Computer Assisted Clincial Medicine, Heidelberg University, Mannheim, Germany, 4University of Minnesota, Minneapolis, MN, United States, 5Working Group on Cardiovascular Magnetic Resonance Imaging, Max-Delbrück-Centrum and Charité -Medical University Berlin, Berlin, Germany, 6Department of Cardiology and Nephrology, HELIOS Klinikum Berlin-Buch, Berlin, Germany

Late Gadolinium Enhancement (LGE) is commonly acquired during a single end-diastolic phase with inversion-recovery contrast that nulls healthy myocardial tissue. In this work, we propose a method for acquisition of cardiac phase-resolved LGE images based on an ECG triggered Look-Locker experiment with continuous FLASH imaging. Semi-quantitative evaluation of this pulsed-inversion recovery allows synthetization of LGE image contrast for all cardiac phases. Accurate functional depiction with temporal resolution up to 60 ms is obtained in healthy subjects at 3T. Images of 20 patients on a clinical 1.5T scanner show promising depiction of focal scar at a temporal resolution of 80ms.

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