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Abstract #0316

An Optimized Single-shot Sequence for Fast T2w Imaging of the Brain

Mahesh Bharath Keerthivasan1,2, Blair Winegar2, Unni Udayasankar2, Ali Bilgin1,3, Maria Altbach2, and Manojkumar Saranathan2

1Electrical and Computer Engineering, University of Arizona, Tucson, AZ, United States, 2Medical Imaging, University of Arizona, Tucson, AZ, United States, 3Biomedical Engineering, University of Arizona, Tucson, AZ, United States

T2-weighted imaging of the brain using single shot sequences such as HASTE suffer from reduced spatial resolution, blurring artifacts and decreased conspicuity of small lesions. We present an analytic framework to design the refocusing flip angles for the HASTE sequence tailored for brain imaging. The flip angles are optimized to minimize SAR and blurring, and maximize SNR. The utility of this sequence is demonstrated by incorporating it in a brain tumor protocol and comparing its performance to conventional T2w Turbo Spin Echo in 21 patients.

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