Abstract #0333

Subregional bone marrow adipose tissue composition in the proximal femur: Comparison of 3T Chemical Shift Encoded-MRI and Magnetic Resonance Spectroscopy

Dimitri MARTEL¹, Benjamin LEPORQ², Mary BRUNO¹, Stephen HONIG³, Amit SAXENA⁴, H.Michael BELMONT⁴, Gabrielle TURYAN¹, Ravinder R. REGATTE¹, and Gregory CHANG¹

¹Radiology, NYU Langone Health, New York, NY, United States, ²Université de Lyon; CREATIS CNRS UMR 5220, Inserm U1206, INSA-Lyon, UCBL Lyon 1, Villeurbanne, France, ³Osteoporosis Center, Hospital for Joint Diseases, NYU Langone Health, New York, NY, United States, ⁴Department of Rheumatology, NYU Langone Health, New York, NY, United States

Studies of bone marrow adipose tissue (bMAT) composition in osteoporosis has revealed increased [a1] in fat content and decreased unsaturated fatty acid in the proximal femur in osteoporosis (OP) patients compared to controls. Advancements in MR image-based methods for fat assessment have allowed quantification of fat content though chemical-shift encoded MRI (CSE-MRI). CSE-MRI methods have not been compared to MRS for bMAT composition assessment. The aim of this study was to quantify, within subregions of the proximal femur, bone marrow PDFF as well as saturated and unsaturated fat using both CSE-MRI and MRS.

How to access this content:

For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.

After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.

After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.

Click here for more information on becoming a member.