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Abstract #0360

Feasibility of absolute myocardial blood flow quantification using Simultaneous Multi Slice (SMS) SSFP first-pass myocardial perfusion imaging and iterative reconstruction at 1.5 Tesla.

Muhummad Sohaib Nazir1, Radhouene Neji1,2, Peter Speier3, Daniel Staeb4, Michaela Schmidt3, Christoph Forman3, Reza Razavi1, Sven Plein1, Tevfik Ismail1, Sebastien Roujol1, and Amedeo Chiribiri1

1Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, 2MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom, 3Siemens Healthcare, Erlangen, Germany, 4The Centre for Advanced Imaging, The University of Queensland, Brisbane, Australia

Quantification of myocardial blood flow (MBF) enhances diagnosis and provides prognostic information. Simultaneous Multi Slice (SMS) imaging allows greater spatial coverage of the heart with minimal signal-to-noise penalty and is thus desirable for perfusion imaging. 5 patients underwent two rest perfusion scans using a dual-bolus technique with SMS protocol (6 slices) and iterative reconstruction and standard 3 slice bSSFP sequence. Absolute MBF was quantified with a fermi-constrained deconvolution algorithm. Global and territorial MBF was comparable between the different methods. Future evaluation in patients with stress testing and greater heart coverage may provide clinical utility in patients with coronary artery disease.

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