Abstract #0366

Assessment of Regional Myocardial Velocities by Tissue Phase Mapping and Feature Tracking in Healthy Children and Pediatric Patients with Hypertrophic Cardiomyopathy: A Comparison Study

Alexander Ruh¹, Arleen Li², Joshua D Robinson^1,3,4, Cynthia K Rigsby^1,4,5, and Michael Markl^1,6

¹Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States, ²Feinberg School of Medicine, Northwestern University, Chicago, IL, United States, ³Department of Pediatrics, Division of Pediatric Cardiology, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, United States, ⁴Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States, ⁵Department of Medical Imaging, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, United States, ⁶Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Chicago, IL, United States

In this study, we compare tissue phase mapping (TPM) and feature tracking (FT) of standard cine SSFP images for the assessment of regional myocardial velocities in 15 pediatric patients with hypertrophic cardiomyopathy (HCM) and 20 age-matched healthy controls. Data analysis included the calculation of segmental (AHA 16-segment model) left ventricular radial and long-axis peak velocities in systole and diastole. Both techniques detected significantly decreased diastolic velocities in HCM patients compared to controls, suggesting reduced myocardial relaxation despite normal ejection fraction. Lower temporal resolution of FT derived velocities resulted in systematically lower peak velocities compared to directly measured TPM velocities.

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