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Abstract #0517

Evaluation of Four T1 Mapping Sequences for Obtaining the Extracellular Volume Fraction in Abdominal Imaging

Temel Tirkes1, Chen Lin2, Xuandong Zhao3, Dominik Nickel4, Kelvin Chow5, Alex J Stuckey3, Robert Grimm4, and Shivraman Giri6

1Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, United States, 2Indiana University School of Medicine, Indianapolis, IN, United States, 3Radiology and Clinical Sciences, Indiana University School of Medicine, Indianapolis, IN, United States, 4MR Application Predevelopment, Siemens Healthcare, Erlangen, Germany, 5MR R&D Collaborations, Siemens Medical Solutions USA, Inc, Chicago, IL, United States, 6Siemens Medical Solutions, USA Inc, Chicago, IL, United States

Many different T1 mapping sequences and extracellular volume (ECV) fraction have proven to be useful tools for evaluation of tissue fibrosis, however their potential has not been explored in abdominal imaging. We evaluated 4 different T1 mapping techniques; Dual-flip angle VIBE (DFA VIBE), MOLLI, SASHA and IR-SNAPSHOT and obtained similar ECV fractions of the liver and pancreas. DFA VIBE has the highest spatial coverage in 1 breath hold but suffers from inhomogeneous T1 in the aortic blood. IR-SNAPSHOT has advantage of not requiring cardiac gating and provides the most homogenous T1 of the blood within the aorta.

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