Our purpose was to develop a robust method for joint quantification of water and fat fractions as well as fatty acid maps from bipolar multi-echo MR data. Its accuracy and reproducibility across field strengths and sequences was demonstrated using an oil phantom. Repeated in-vivo breath-hold acquisitions in n = 11 patients yielded median absolute differences of 4.8%, 1.0% and 8.2% for the saturated, mono-unsaturated and poly-unsaturated fat components in the liver, spleen and subcutaneous, perirenal and mesenteric fat depots.
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