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Abstract #0572

Deep learning MR reconstruction with Automated Transform by Manifold Approximation (AUTOMAP) in real-world acquisitions with imperfect training

Bo Zhu1,2, Berkin Bilgic1, Congyu Liao1, Bruce R. Rosen1, and Matthew S Rosen1,2

1A.A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States, 2Department of Physics, Harvard University, Cambridge, MA, United States

Automated Transform by Manifold Approximation (AUTOMAP) is a generalized MR image reconstruction framework based on supervised manifold learning and universal function approximation implemented with a deep neural network architecture. Here we investigate the effect of significant sampling trajectory error in spiral acquisitions, where mismatch between training and runtime scanner trajectories may result in unpredictable reconstruction artifacts. We demonstrate through Monte Carlo analysis that the error in AUTOMAP reconstruction increases smoothly as a function of trajectory error, demonstrating reasonable robustness to trajectory deviation. We find these simulation results are consistent with reconstruction performance on real scanner data acquired from human subjects.

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