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Abstract #0608

Dietary intervention can induce changes in hepatic fat content during the day detectable by MR spectroscopy

Monika Dezortova1, Tereza Blahova1, Miloslav Drobny1, Petr Sedivy1, Jan Kovar1, and Milan Hajek1

1MR-Unit, Dept. Diagnostic and Interventional Radiology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic

We analyzed in vivo hepatic fat content changes during the day under different dietary interventions (fasting, fat alone, fat + fructose, fat + glucose, and glucose alone). Single voxel 1H MR spectroscopy of the liver in ten healthy volunteers was used at 3T MR system. We demonstrated that it is possible to induce the hepatic fat content changes by appropriately chosen dietary interventions and that such changes can be detected noninvasively by 1H MR spectroscopy.

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