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Abstract #0615

Quantitative Characterization of the Motion Sensitivity of Stimulated Echo Diffusion-weighted Imaging in the Liver

Yuxin Zhang1,2, James Holmes2, Kevin Johnson1,2, Ty Cashen3, and Diego Hernando1,2

1Medical Physics, University of Wisconsin Madison, Madison, WI, United States, 2Radiology, University of Wisconsin Madison, Madison, WI, United States, 3Global MR Applications & Workflow, GE Healthcare, Madison, WI, United States

STimulated Echo (STE) DWI is able to provide high b values with moderate echo times by increasing the mixing time (TM). However, long TM in STE-DWI also lead to increased sensitivity to bulk motion. To understand the tradeoff between SNR and motion sensitivity of STE DWI, this study assessed the quantitative relationship between TE, TM, and motion sensitivity in the liver with simulation and in-vivo experiments. As a result, the SNR and high motion sensitivity present an important trade-off with STE-DWI. In addition, when moment-nulling is used to compensate motion, the advantage of decreased TE from STE will be lost.

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