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Abstract #0656

Construction of Spatiotemporal Infant Cortical Surface Atlas of Rhesus Macaque

Fan Wang1, Chunfeng Lian1, Jing Xia1, Zhengwang Wu1, Dingna Duan1, Li Wang1, Dinggang Shen1, and Gang Li1

1Department of Radiology and BRIC, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States

Rhesus macaque is a widely used animal model helping understand neural development in the human brain. Available adult macaque brain atlases are not suitable for infant studies, due to their dramatic brain difference. Building age-matched atlases is thus highly desirable yet still lacking. In this study, using MRI scans for 32 healthy rhesus monkeys, we constructed the first spatiotemporal cortical surface atlas for macaques aged from 2 weeks to 24 months, which were further equipped with developmental-trajectory-based parcellation maps. These surface atlases and parcellation maps will greatly facilitate the early brain development studies of macaques.

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