This study demonstrated a method for 3D simultaneous relaxometry and segmentation of human brain tissues through a deep neural network. Ranges of T1 and T2 values for gray matter, white matter and cerebrospinal fluid (CSF) were used as the prior knowledge. The proposed method can directly generate brain T1 and T2 maps in conjunction with segmentation of gray matter, white matter and CSF, and in particular was robust for relaxometry/segmentation in the challenging region of deep brain nuclei.
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