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Abstract #0682

Repeatability of 2D FISP MR Fingerprinting in the Brain at 1.5T and 3.0 T

Guido Buonincontri1,2, Laura Biagi1,3, Alessandra Retico2, Michela Tosetti1,3, Paolo Cecchi4, Mirco Cosottini1,4,5, Pedro A Gómez6, Rolf F Schulte7, Mary McLean8, Frank Riemer9, Ferdia Gallagher9, Martin J Graves9, and Joshua D Kaggie9

1IMAGO7 Foundation, Pisa, Italy, 2National Institute for Nuclear Physics, Pisa, Italy, 3IRCCS Fondazione Stella Maris, Pisa, Italy, 4Unit of Neuroradiology, AOUP, Pisa, Italy, 5Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy, 6Department of Computer Science, Technische Universitat Munchen, Munich, Germany, 7GE Healthcare, Munich, Germany, 8Cancer Research UK Cambridge Institute, University of Cambridge, UK, Cambridge, United Kingdom, 9Department of Radiology, University of Cambridge, Cambridge, United Kingdom

MR Fingerprinting is a new multi-contrast imaging method that is appealing for its ability to acquire multiple quantitative maps efficiently when compared to other repeated acquisitions varying a single parameter at a time. This work shows our first demonstration of MRF in vivo repeatability through test/re-test imaging of seven healthy human volunteers at 1.5T and 3.0T. We found the group root-mean-square-difference (NRMSD) of MRF-SSFP T1 measurements to be 5-6% in grey and white matter at 1.5T and 4-5% at 3.0T, T2 NRMSD to be 6-9% at 1.5T and 11-13% at 3.0T, and PD NRMSD to be 2-3% at 1.5T and 2-3% at 3.0T.

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