Abstract #0690

Hemodynamic Assessment of the Post-Myocardial Infarction Left Ventricle with 4D Flow MRI

Philip A Corrado¹, Niti R Aggarwal², Jacob A Macdonald¹, Jonathan W Weinsaft^3,4, Christopher J Francois^2,5, and Oliver Wieben^1,5

¹Medical Physics, University of Wisconsin-Madison, Madison, WI, United States, ²Medicine, University of Wisconsin-Madison, Madison, WI, United States, ³Medicine, Weill Cornell Medical College, New York, NY, United States, ⁴Radiology, Weill Cornell Medical College, New York, NY, United States, ⁵Radiology, University of Wisconsin-Madison, Madison, WI, United States

This work employed high resolution time resolved (4D) flow cardiac MRI (CMR) to characterize altered left ventricular (LV) flow physiology after anterior myocardial infarction (MI). 4D Flow CMR was used to quantify LV velocity (parallel to the LV long axis) at pre-specified landmarks in the basal, mid, and apical LV. Post-MI patients with impaired global LV function had reduced peak systolic velocity in all regions compared to age-matched controls (p<0.05). A difference in flow patterns between the LV base and apex was also discerned in post-MI patients, characterized by a marked reduction and prolongation of forward flow in the apex.

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