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Abstract #0698

Brain Tissue Segmentation and Subcortical Parcellation: How Reliable Are Different Tools?

Ariane Fillmer1, Andre Kuehne2, Laura Goeschel3, Theresa Köbe3, Agnes Flöel3,4, and Bernd Ittermann1

1Physikalisch-Technische Bundesanstalt (PTB), Berlin, Germany, 2MRI.Tools GmbH, Berlin, Germany, 3Department of Neurology, Charité - Universitätsmedizin Berlin, Berlin, Germany, 4Department of Neurology, University Medicine Greifswald, Greifswald, Germany

Volume based morphometry is a well-established tool to investigate changes of brain structures in neurodegenerative diseases, and a variety of implementations is available. With MRI investigations as an indispensable instrument for diagnosis and disease progress monitoring, the question about reliability and robustness of these tools arises. This work examines the accuracy of CAT 12 and FreeSurfer by comparing a selection of their calculated subcortical volumes to a ground truth.

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