Meeting Banner
Abstract #0710

Turbo VSASL: slice- and velocity-selective ASL for high temporal resolution functional CBF mapping

Divya S Bolar1,2, Jonathan Polimeni1,2, Ned Ohringer1,2, Elfar Adalsteinsson3, and Bruce R Rosen1,2

1MGH/HST Martinos Center for Biomedical Imaging, Charlestown, MA, United States, 2Radiology, Massachusetts General Hospital, Boston, MA, United States, 3Electrical Engineering and Computer Science, MIT, Cambridge, MA, United States

Velocity selective (VS) ASL theoretically allows high temporal resolution functional CBF mapping, since the arterial tag is immediately delivered to target microvascultature. This is in contrast to conventional ASL, which suffers from transit delays that limit minimum TR to about one second. VSASL, however, employs a nonselective VS tagging scheme, resulting in incomplete T1 recovery of tagged blood away from the imaging slice, and subsequent signal loss at low TRs. In this study, we introduce a slice-selective VS tag to mitigate T1 recovery effects, and for the first time demonstrate subsecond functional CBF mapping of the visual cortex. The approach is dubbed “Turbo VSASL”.

This abstract and the presentation materials are available to members only; a login is required.

Join Here