We report increase in sensitivity, specificity and accuracy of PIRADSv2 by addition of MRSI to mpMRI protocol for detection of cancer of prostate (CaP). 26 patients having a biopsy-proven CaP, were investigated at 3.0T using mpMRI including MRSI, followed by radical prostatectomy within 1 month. PIRADSv2 score for mpMRI, PIRADSv1 score for MRSI and Gleason grade group from radical prostatectomy specimens were determined. ROC curve analysis was used to determine the accuracy for cut-offs. A combination of MRSI PIRADSv1 cut-off ≥4 and PIRADSv2 cut-off ≥3 showed the best accuracy (96.2%) for CaP detection. When MRSI was added to PIRADSv2 scoring we found an improvement from 71.4% sensitivity and 91.9% specificity of PIRADSv2 to 91.8% sensitivity and 98% specificity for detecting CaP.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords