Abstract #0717

Delineation accuracy of prostate cancer for focal therapy: comparison of MR imaging and histopathology characteristics

Petra J van Houdt¹, Ghazaleh Ghobadi¹, Stijn W Heijmink², Ivo Schoots², Jeroen de Jong³, Iris Walraven¹, Henk G van der Poel⁴, Floris J Pos¹, Susanne Rylander⁵, Lise N Bentzen⁶, Karin Haustermans⁷, and Uulke A van der Heide¹

¹Radiation Oncology, the Netherlands Cancer Institute, Amsterdam, Netherlands, ²Radiology, the Netherlands Cancer Institute, Amsterdam, Netherlands, ³Pathology, the Netherlands Cancer Institute, Amsterdam, Netherlands, ⁴Urology, the Netherlands Cancer Institute, Amsterdam, Netherlands, ⁵Medical Physics, Aarhus University Hospital, Aarhus, Denmark, ⁶Oncology, Aarhus University Hospital, Aarhus, Denmark, ⁷Radiation Oncology, University Hospitals Leuven, Leuven, Belgium

The success of any focal therapy for prostate cancer relies on accurate tumor detection and delineation. Currently there are no guidelines for delineation of prostate tumors. In this study we showed that radiologists are better in delineating parts of tumors with Gleason pattern 4 and 5 than Gleason pattern 3, but still the sensitivity (0.56) needs to be improved for focal therapy and volume estimation.

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