This study aims to provide to the research community quantitative measurements about the axon diameter overestimation due to the straight-cylinder assumption usually made in state-of-the-art models for diameter mapping with DW-MRI. Our methodology uses a Monte Carlo diffusion simulator to compute the diffusion weighted magnetic resonance signals of undulating axons. We use in our experiments plausible tissue values, we also explore a broad parameter set that depicts undulation. The results of this study provide useful information to understand the differences between the estimators from histology vs. the estimated diameters when using the model assumption of simple shaped axons.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords