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Abstract #0859

Identifying ischemic zone patterns and origins using multi-delay arterial spin labeling in vasospasm

Swati Rane1, Daniel Hippe1, Michael Levitt1, Louis Kim1, and Jalal B Andre1

1University of Washington Medical Center, Seattle, WA, United States

Our goal was to evaluate a multi-delay, pseudocontinuous arterial spin labeling (ASL) approach to detect focal delayed cerebral ischemia in patients with vasospasm. We show that inferences on vascular origins based on ASL and standardized perfusion territories correlated well with expert reader reads that rely on an invasive catheter-based digital subtraction angiography (DSA) examination. Importantly, ASL identified possible ischemic zones due to distal vasospasm, which are nearly undetectable on conventional DSA. Thus, use of ASL may prevent unnecessary DSA examinations and improve patient prognosis.

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