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Abstract #0918

Whole-Heart Cartesian Coronary MRA with Sub-Millimeter Isotropic Resolution in Four-Minute Acquisition

Aurelien Bustin1, Giulia Ginami1, Imran Rashid1, Teresa Correia1, Tevfik Ismail1, Radhouene Neji1,2, Rene Botnar1, and Claudia Prieto1

1Biomedical Engineering Department, King's College London, London, United Kingdom, 2Siemens Healthcare Limited, Frimley, United Kingdom

Whole-heart coronary magnetic resonance angiography (CMRA) with isotropic resolution allows reformatting in any desired imaging plane without loss of resolution. However, achieving sub-millimeter isotropic resolution with a conventional 1D diaphragmatic navigator gated CMRA is very challenging due to long and unpredictable scan times. In this study, we sought to achieve sub-millimeter CMRA by combining 2D image-based navigator motion correction with highly accelerated compressed sensing reconstruction in concert with variable density Cartesian spiral-like k-space sampling to significantly accelerate the scan. The proposed technique enables CMRA acquisitions with 0.9mm isotropic spatial resolution in about 4 minutes. Ultimately, this technique might be useful for rapid screening of the coronaries in patients with suspected coronary artery disease.

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