Meeting Banner
Abstract #0945

MRI Compatible Hypobaric Chamber to study Early Aeromedical Evacuation Following Traumatic Brain Injury

Su Xu1, Sijia Guo1, Steven Roys1, Julie L Proctor2, Gary Fiskum2, and Rao Gullapalli1

1Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, MD, United States, 2Department of Anesthesiology and the Center for Shock Trauma and Anesthesiology Research, University of Maryland School of Medicine, Baltimore, MD, United States

Combat-related TBI leads to significant mortality and morbidity. In our previous research, we have demonstrated that simulated aeromedical evacuation (AE), or hypobaria, worsens neurological outcomes after TBI and suggests that early AE of TBI patients contributes to secondary insults. To study the effects of such hypobaric exposure during early stage of injury we have constructed a MRI compatible hypobaric chamber that allows us to evaluate changes in metabolism, perfusion, and functional status in a preclinical model of brain injury. Here we demonstrate our initial experiences with the hypobaric chamber in the MRI to obtain in vivo imaging and spectroscopic data.

This abstract and the presentation materials are available to members only; a login is required.

Join Here