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Abstract #1005

3D ultrasound based motion tracking combined with rapid multislice MR-thermometry for MR guided HIFU on mobile organs.

Pierre Bour1,2,3,4, Valéry Ozenne1,2,3, Fabrice Marquet1,2,3, Baudouin Denis de Senneville5, Erik Dumont4, and Bruno Quesson 1,2,3

1IHU-LIRYC, PESSAC, France, 2Univ. Bordeaux, Centre de recherche Cardio-Thoracique de Bordeaux, Bordeaux, France, 3INSERM U1045, Bordeaux, France, 4Image Guided Therapy, Pessac, France, 5Institute of Mathematics of Bordeaux, Bordeaux, France

MRI-guided High Intensity Focused Ultrasound treatment of mobile organs remain challenging in terms of therapy effectiveness (target tracking) and precision of temperature monitoring (motion and related susceptibility artifacts). In this study, we propose to use some elements of the HIFU transducer in reception for a standalone motion correction of the focus position, allowing full flexibility on the MR-Thermometry sequence. The method is validated in vitro on a mobile gel and in vivo in the liver of pig during breathing, with a 10Hz update of the HIFU focus position under rapid and volumetric MR-thermometry.

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