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Abstract #1042

Intravoxel Incoherent Motion (IVIM) Imaging in Human Achilles Tendon

Kenneth T Wengler1, Dharmesh Tank2, Mingqian Huang2, Elaine Gould2, Mark Schweitzer2, and Xiang He2

1Biomedical Engineering, Stony Brook University, Stony Brook, NY, United States, 2Radiology, Stony Brook University Hospital, Stony Brook, NY, United States

Clinically, Achilles tendon (AT) rupture accounts for 40-60% of all operative tendon repairs. AT microcirculation plays a crucial role in the progression of tendinopathy and tendon repair. In this study a novel ste-RESOLVE IVIM protocol was developed to image AT microcirculation. Healthy participants were imaged pre- and post-exercise, and exercised induced increases in blood volume and blood flow were observed. AT tendinopathy patients exhibited greater baseline blood volume and blood flow when compared to healthy participants. For the first time, a robust MRI-based technique was developed to investigate the role of Achilles tendon microcirculation in tendinopathy.

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