Meeting Banner
Abstract #1090

Tensor-valued diffusion MRI in under 3 minutes: An initial survey of microscopic anisotropy and tissue heterogeneity in four brain tumor types

Markus Nilsson1, Filip Szczepankiewicz1,2, Carl-Fredrik Westin3, Alexandra Golby3, Danielle van Westen1, and Pia C Sundgren1

1Clinical Sciences Lund, Radiology, Lund University, Lund, Sweden, 2Random Walk Imaging, Lund, Sweden, 3Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States

Microscopic diffusion anisotropy and tissue heterogeneity are two independent features of tumor microstructure that can be probed by diffusion MRI but only by using so-called b-tensor encoding. These independent features reflect cell shapes and cell density variance in tumors. Here, we demonstrate high-quality maps of these features, derived from data acquired in only 3 minutes, in patients with various brain tumor histologies. Several remarkable features were observed which suggest that the maps may contribute valuable diagnostic information, in particular since the features vary both within and between tumors.

This abstract and the presentation materials are available to members only; a login is required.

Join Here