Resting-state fMRI has been widely used to map brain network dynamics via sliding-window correlations between regional functional signals. Using frame-wise clustering of spontaneous BOLD fMRI, here we map the dynamics of brain-wide network activity in the mouse brain with voxel-resolution, at the subject and group level, without the need to use pre-imposed regional parcellation or correlation windows. This approach revealed a reproducible set of recurrent brain states encompassing previously defined functional connectivity networks, which happen at specific phases of global fMRI signal oscillations. Our results provide a novel interpretative framework for the emergence and organization of brain-wide network dynamics.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords