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Abstract #1147

Correlating Proteoglycan Concentration in Intervertebral Discs Using 1H MR Spectroscopy with Lumber Lordotic Angle

Lisa Maria Harris1,2, Joely Smith1, Ella Hodder3, Michael Mills1, Janice Bush2, Vincent Pelling1, Mara Cercignani2, and Nicholas Dowell2

1Radiological Science, Brighton and Sussex University Hospitals NHS Trust, Brighton, United Kingdom, 2Clinical Imaging Sciences Centre, Brighton Sussex Medical School, Brighton, United Kingdom, 3Computing, Engineering and Mathematics, University of Brighton, Brighton, United Kingdom

Both proteoglycan (PG) concentration and lumbar lordotic (LL) angle are linked with the health of spinal discs. Previously, it has been shown that PG concentration can reliably be measured using 1H MR Spectroscopy at 1.5T and that PG concentration is higher in female discs compared with male discs. This study has now been extended to show a correlation between PG and LL angle in a group of female participants.

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