DSC-MRI is the most common approach used for brain tumor perfusion imaging. Consensus is being reached regarding a recommended method for data acquisition, one that requires a contrast agent preload and the application of leakage correction. However, recent simulations suggest that if a low flip angle is used for DSC-MRI data collection then a contrast agent preload might not be necessary. In this study DSC-MRI data collected in 19 patients with brain tumors supports this hypothesis and further suggests that the application of leakage correction as well as a standardization algorithm further improves the results.
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