Osteoporosis (OP) is due to weak bone and can ultimately lead to fracture. Recent findings shows link between bone marrow adipose tissue (bMAT) composition and amount and OP. OP can be induced by drugs such as glucocorticoids resulting in glucocorticoid-induced osteoporosis (GIO) and can affect energy metabolism pathways, induce changes in bone including increased total marrow adiposity and changes in bMAT composition. The composition of bMAT in GIO has not been previously investigated. Our aim was to assess the bMAT composition of a GIO population and compare it to OP patients using 3T Chemical Shift Encoded- MRI (CSE-MRI).
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