Materials such as biological tissue are often characterized by considerable heterogeneity. This can manifest itself in significant variability of certain physicochemical parameter values across the measured volume. If the chemical shift of a particular MR resonance varies systematically with such a parameter, the resulting lineshape can be used to quantitatively characterize the heterogeneity with respect to this parameter. This is achieved by transforming the MRS lineshape into a curve representing the statistical distribution of the parameter values in question, followed by the derivation of a histogram. We study here two important conditions for the statistical evaluation of such spectrum-derived histograms.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Keywords